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2) mitotic index was used instead of Clark level of invasion for patients with thin primary tumors

Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation

When the GSH concentration in the dialysis medium was 2 M, the cumulative release of GNA after 72 h increased to 18.6%, indicating that the disulfide bonds remained largely intact at low reductant concentrations, allowing for effective drug retention during blood circulation